Fluvoxamine

Fluvoxamine (brand name Luvox)

(Trade Names: Luvox and Faverin)

Fluvoxamine was the first non-Tricyclic antidepressant (TCA) drug approved by the U.S. Food and Drug Administration (FDA), specifically for the treatment of OCD, in 1993.

Form: tablets.
Children: The NICE guidelines for treating OCD report that Fluvoxamine has a UK Marketing Authorisation for use in OCD in children 8 years and older (November 2005).
Fluvoxamine has a UK marketing authorisation for treating OCD in children aged 8 years and older.
Adult dose: 50 mg at bedtime, increase gradually in steps of 50 mg up to a maximum of 300 mg/day. If there is no improvement within 10 weeks, it should be reviewed.
Half-life: 15.6 hours
Drug interactions: Monoamine oxidase inhibitors (MAOI) should not be given until at least five weeks after stopping Fluvoxamine. It also interacts with the asthma drugs theophylline and aminophylline.
Withdrawal: Avoid abrupt withdrawal.

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